PeptideDB

[Pro9]-Substance P

CAS: 104486-69-3 F: C66H102N18O13S W: 1387.69

-Substance P is a potent, reversible and selective agonist of NK-1 tachykinin receptors with an EC50 of 0.93 nM.
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Bioactivity [Pro9]-Substance P is a potent, reversible and selective agonist of NK-1 tachykinin receptors with an EC50 of 0.93 nM[1].
Invitro [3H][Pro9]-Substance P can be used as a radio ligand for NK- 1 binding sites[1].[Pro9]-Substance P stimulates inositol phosphate formation with an efficacy only slightly lower than that of SP (EC50 values of 0.93 ± 0.07 and 0.45 ± 0.06 nM, respectively) on primary cultures of newborn mouse cortical glial cells[1].
Name [Pro9]-Substance P
CAS 104486-69-3
Shortening RPKPQQFFPLM-NH2
Formula C66H102N18O13S
Molar Mass 1387.69
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.